An investigation of the hepatoprotective effects of Mollugo ceroviana Linn on rats subjected to carbon trifluoride-induced liver damage

Abstract

There is no specific treatment regimen for liver damage induced by pathogens or chemical reagents, despite the fact
that the two are quite comparable. The majority of substances that are harmful to the liver do so primarily by causing
oxidative damages, such as lipid peroxidation. Because there was no effective allopathic treatment for hepatic
damage, the researcher felt compelled to investigate herbal remedies. So, we have tried to determine how effective
Mollugo cerviana is as a hepatoprotective agent. In this study, we looked at the effects of an alcoholic extract of
Mollugo cerviana on CCl4-induced liver damage. The findings showed that CCl4-treated rats had considerably
higher levels of all the enzymes compared to the control group. A positive control was used using silymarin at a
dosage of 25 mg/kg. The antioxidant enzyme activities of rats treated with Mollugo cerviana were likewise
significantly elevated. Lipid peroxidation is reduced and free radical scavenging is enhanced as a result of the
antioxidant defenses provided by these enzymes. The substantial hepatoprotective effect may be due to the presence
of flavonoids in the extract.